Tube1 | tubulin, epsilon 1

GeneMGI:1919174Synonyms: 2310061K05Rik

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetTube1em1(IMPC)HmguheterozygoteEarly adult7x10-8 
hyperactivity1 supporting datasetTube1em1(IMPC)HmguheterozygoteEarly adult1.11x10-5 
preweaning lethality, complete penetrance1 supporting datasetTube1em1(IMPC)HmguhomozygoteEarly adultN/A * 
decreased thigmotaxis2 supporting datasetsTube1em1(IMPC)HmguheterozygoteEarly adult8.01x10-9 
decreased anxiety-related response1 supporting datasetTube1em1(IMPC)HmguheterozygoteEarly adult1.28x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tube1em1(IMPC)HmguExon Deletionmouse
Tube1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Tube1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Tube1tm81944(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Tube1tm81944(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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