Antxr2 | anthrax toxin receptor 2

GeneMGI:1919164Synonyms: CMG2, CMG-2, +2 more

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetAntxr2em1(IMPC)WtsihomozygoteEarly adult4.33x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetAntxr2em1(IMPC)WtsihomozygoteEarly adult1.59x10-6 
increased circulating alkaline phosphatase level1 supporting datasetAntxr2em1(IMPC)WtsihomozygoteEarly adult1.49x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Antxr2em1(IMPC)WtsiPoint Mutationmouse
Antxr2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Antxr2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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