Coq2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Skeleton Cardiovascular system Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| decreased heart weight | 1 supporting dataset | Coq2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.12x10-5 | ||
| increased total body fat amount | 2 supporting datasets | Coq2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.1x10-7 | ||
| decreased bone mineral content | 2 supporting datasets | Coq2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.7x10-8 | ||
| decreased lean body mass | 1 supporting dataset | Coq2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.8x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Coq2tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Coq2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Coq2.
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| Coq2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Coq2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Coq2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |