Acsl5 | acyl-CoA synthetase long-chain family member 5

GeneMGI:1919129Synonyms: 1700030F05Rik, Facl5

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating glucose level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.16x10^-6
decreased circulating cholesterol level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.02x10^-11
decreased circulating total protein level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.39x10^-5
decreased liver weight	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.73x10^-9
increased circulating bilirubin level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.21x10^-7
decreased circulating triglyceride level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.19x10^-6
increased heart weight	2 supporting datasets	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.22x10^-5
cornea opacity	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.87x10^-9
increased spleen weight	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.8x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Acsl5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.72x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acsl5.

Associated images

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Histopathology

There is no histopathology data found for Acsl5.

IMPC related publications

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External links

No external links available for Acsl5.

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*Acsl5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Acsl5^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Acsl5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Acsl5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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