Fam83d | family with sequence similarity 83, member D

GeneMGI:1919128Synonyms: 2310007D09Rik

Physiological systems

21 / 24 physiological systems tested

12 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

9 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:14Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adult8.54x10-6 
abnormal skin morphology2 supporting datasetsFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
anophthalmia2 supporting datasetsFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased startle reflex1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adult7.03x10-9 
abnormal heart morphology1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased prepulse inhibition4 supporting datasetsFam83dem1(IMPC)CcpczhomozygoteEarly adult1.47x10-5 
enlarged heart1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adult8.91x10-6 
abnormal testis morphology1 supporting datasetFam83dem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam83dem1(IMPC)CcpczExon Deletionmouse
Fam83dtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fam83dtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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