Fam83d | family with sequence similarity 83, member D
Physiological systems
21 / 24 physiological systems tested
12 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system
9 No significant impact
3 Not tested
Data collections
Gene metrics:14Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased fasting circulating glucose level | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | 8.54x10-6 | ||
abnormal skin morphology | 2 supporting datasets | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
anophthalmia | 2 supporting datasets | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
decreased startle reflex | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | 7.03x10-9 | ||
abnormal heart morphology | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
decreased prepulse inhibition | 4 supporting datasets | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | 1.47x10-5 | ||
enlarged heart | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal thymus morphology | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
increased circulating aspartate transaminase level | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | 8.91x10-6 | ||
abnormal testis morphology | 1 supporting dataset | Fam83dem1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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External links
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Fam83dem1(IMPC)Ccpcz | Exon Deletion | | mouse |
Fam83dtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Fam83dtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |