Serpinb12 | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12

GeneMGI:1919119Synonyms: 2300003F07Rik, 4833409F13Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Limbs/digits/tail Behavior/neurological Skeleton

16 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

short tibia1 supporting datasetSerpinb12tm1b(KOMP)WtsihomozygoteEarly adult6.73x10-6 
head bobbing1 supporting datasetSerpinb12tm1b(KOMP)WtsihomozygoteEarly adult3.15x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoten/a0% (0/2)0.86% (5/579)
brainstemheterozygoten/a0% (0/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
esophagusheterozygoten/a100% (2/2)1.67% (7/419)
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Histopathology

IMPC related publications

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Serpinb12tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Serpinb12tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Serpinb12tm41561(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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