Fbxo30 | F-box protein 30

GeneMGI:1919115Synonyms: 1700026A16Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased circulating glucose level	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1x10^-5
increased prepulse inhibition	2 supporting datasets	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.66x10^-5
improved glucose tolerance	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.87x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.99x10^-5
decreased startle reflex	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.06x10^-5
increased bone mineral content	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.36x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.58x10^-5
increased bone mineral density	1 supporting dataset	Fbxo30^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.64x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo30.

Associated images

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Histopathology

There is no histopathology data found for Fbxo30.

IMPC related publications

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External links

No external links available for Fbxo30.

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*Fbxo30^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fbxo30^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fbxo30^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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