Plekhf2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2

GeneMGI:1919051Synonyms: ZFYVE18, 1110070J07Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hearing/vestibular/ear Hematopoietic system Behavior/neurological Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	2 supporting datasets	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	2.53x10^-8
increased circulating unsaturated transferrin level	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	2.42x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	6.52x10^-6
decreased mean corpuscular hemoglobin	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	3.39x10^-15
increased eosinophil cell number	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	8.61x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	3.96x10^-5
decreased circulating cholesterol level	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	3.49x10^-5
decreased mean corpuscular volume	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	3.85x10^-19
small kidney	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Plekhf2^{em1(IMPC)Wtsi}	homozygote	Early adult	3.43x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Plekhf2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Plekhf2.

IMPC related publications

Loading...

External links

No external links available for Plekhf2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Plekhf2^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Plekhf2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Plekhf2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Plekhf2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Plekhf2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes