Isyna1 | myo-inositol 1-phosphate synthase A1

GeneMGI:1919030Synonyms: 1300017C10Rik, myo-inositol 1-phosphate synthase A1, +1 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Embryo Limbs/digits/tail Nervous system Mortality/aging Cardiovascular system Craniofacial

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal pharyngeal arch morphology	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E15.5	N/A ^*
abnormal visceral yolk sac morphology	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal somite shape	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
syndactyly	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E15.5	N/A ^*
pale yolk sac	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Isyna1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal tail bud morphology	1 supporting dataset	Isyna1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Isyna1.

Associated images

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Histopathology

There is no histopathology data found for Isyna1.

IMPC related publications

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External links

No external links available for Isyna1.

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*Isyna1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Isyna1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Isyna1^{tm438165(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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