Klhl5 | kelch-like 5

GeneMGI:1919028Synonyms: 1300013C10Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Skeleton Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:78Adult tissues

27Embryo tissues

Phenotypes

Phy. System:



abnormal coat/hair pigmentation	3 supporting datasets	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.47x10^-10
abnormal lens morphology	1 supporting dataset	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.17x10^-5
abnormal rib morphology	1 supporting dataset	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.11x10^-5
abnormal cornea morphology	1 supporting dataset	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.45x10^-6
abnormal kidney morphology	1 supporting dataset	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Klhl5^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.57x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klhl5.

Associated images

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Histopathology

There is no histopathology data found for Klhl5.

IMPC related publications

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External links

No external links available for Klhl5.

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*Klhl5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Klhl5^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Klhl5^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes