Ap2b1 | adaptor-related protein complex 2, beta 1 subunit
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Digestive/alimentary Behavior/neurological Craniofacial Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cleft palate | 1 supporting dataset | Ap2b1em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ap2b1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased grip strength | 1 supporting dataset | Ap2b1em1(IMPC)J | heterozygote | Early adult | 7.91x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Ap2b1em1(IMPC)J | homozygote | E18.5 | N/A * |
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External links
No external links available for Ap2b1.
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| Ap2b1em1(IMPC)J | Exon Deletion | | mouse |
| Ap2b1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ap2b1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ap2b1tm357351(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |