Pan2 | PAN2 poly(A) specific ribonuclease subunit

GeneMGI:1918984Synonyms: 1200014O24Rik, Usp52

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Cardiovascular system

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased eosinophil cell number	1 supporting dataset	Pan2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.44x10^-5
increased heart weight	1 supporting dataset	Pan2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pan2.

Associated images

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Histopathology

There is no histopathology data found for Pan2.

IMPC related publications

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External links

No external links available for Pan2.

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*Pan2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pan2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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