Osbpl3 | oxysterol binding protein-like 3

GeneMGI:1918970Synonyms: 1200014M06Rik, ORP3, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased lean body mass2 supporting datasetsOsbpl3tm1a(EUCOMM)WtsihomozygoteEarly adult2.43x10-5 
decreased total body fat amount2 supporting datasetsOsbpl3tm1a(EUCOMM)WtsihomozygoteEarly adult1.45x10-6 
increased bone mineral density1 supporting datasetOsbpl3tm1a(EUCOMM)WtsihomozygoteEarly adult1.01x10-5 
increased bone mineral content2 supporting datasetsOsbpl3tm1a(EUCOMM)WtsihomozygoteEarly adult4.63x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Osbpl3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Osbpl3tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Osbpl3tm43446(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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