Tmt1b | thiol methyltransferase 1B

GeneMGI:1918914Synonyms: 0610006F02Rik, Mettl7b

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



decreased circulating chloride level	1 supporting dataset	Tmt1b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.88x10^-5
decreased circulating glucose level	1 supporting dataset	Tmt1b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.96x10^-6
abnormal coat/hair pigmentation	2 supporting datasets	Tmt1b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.95x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmt1b.

Associated images

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Histopathology

There is no histopathology data found for Tmt1b.

IMPC related publications

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External links

No external links available for Tmt1b.

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*Tmt1b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Tmt1b^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Tmt1b^{tm415983(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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