Piezo2 | piezo-type mechanosensitive ion channel component 2

GeneMGI:1918781Synonyms: Fam38b, 9430028L06Rik, +3 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Piezo2^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	Piezo2^em2(IMPC)J	heterozygote	Early adult	7.33x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Piezo2^em2(IMPC)J	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Piezo2^em2(IMPC)J	homozygote	E18.5	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Piezo2^em2(IMPC)J	heterozygote	Early adult	7.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Piezo2.

Associated images

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Histopathology

There is no histopathology data found for Piezo2.

IMPC related publications

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External links

No external links available for Piezo2.

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*Piezo2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Piezo2^em2(IMPC)J*	Exon Deletion	‌	mouse
*Piezo2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Piezo2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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