Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

GeneMGI:1918764Synonyms: 2810416M14Rik, 5730453G22Rik, +5 more

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Craniofacial

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating amylase level	1 supporting dataset	Sfpq^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.47x10^-5
abnormal snout morphology	1 supporting dataset	Sfpq^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sfpq.

Associated images

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Histopathology

There is no histopathology data found for Sfpq.

IMPC related publications

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External links

No external links available for Sfpq.

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*Sfpq^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Sfpq^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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