Usp19 | ubiquitin specific peptidase 19

GeneMGI:1918722Synonyms: 8430421I07Rik

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Integument Growth/size/body region Hematopoietic system Mortality/aging

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Usp19^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.24x10^-5
increased lean body mass	1 supporting dataset	Usp19^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.66x10^-5
abnormal coat appearance	3 supporting datasets	Usp19^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.3x10^-8
increased mean corpuscular hemoglobin	1 supporting dataset	Usp19^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.14x10^-5
male infertility	1 supporting dataset	Usp19^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Usp19^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp19.

Associated images

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Histopathology

There is no histopathology data found for Usp19.

IMPC related publications

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External links

No external links available for Usp19.

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*Usp19^{tm186104(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Usp19^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Usp19^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Usp19^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Usp19^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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