Epg5 | ectopic P-granules 5 autophagy tethering factor

GeneMGI:1918673Synonyms: 5430411K18Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Limbs/digits/tail Nervous system Hematopoietic system Behavior/neurological Skeleton

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:23Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition4 supporting datasetsEpg5em1(IMPC)HhomozygoteEarly adult2.61x10-14 
increased monocyte cell number2 supporting datasetsEpg5em1(IMPC)HhomozygoteEarly adult5.89x10-29 
increased neutrophil cell number2 supporting datasetsEpg5em1(IMPC)HhomozygoteEarly adult6.32x10-21 
decreased circulating glucose level1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult8.68x10-5 
hyperactivity8 supporting datasetsEpg5em1(IMPC)HhomozygoteEarly adult2.39x10-18 
increased basophil cell number1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult1.7x10-6 
decreased lymphocyte cell number1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult4.23x10-11 
increased circulating alkaline phosphatase level1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult1.24x10-25 
decreased startle reflex1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult8.47x10-6 
increased spleen weight1 supporting datasetEpg5em1(IMPC)HhomozygoteEarly adult1.99x10-20 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Epg5em1(IMPC)HExon Deletionmouse

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