Tprg1 | transformation related protein 63 regulated 1

GeneMGI:1918588Synonyms: 5430420C16Rik, Tprg

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal gallbladder morphology1 supporting datasetTprg1em1(IMPC)MbphomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetTprg1em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged gallbladder1 supporting datasetTprg1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetTprg1em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetTprg1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tprg1em1(IMPC)MbpExon Deletionmouse
Tprg1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tprg1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tprg1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Tprg1tm41872(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Tprg1tm41872(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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