Pmpca | peptidase (mitochondrial processing) alpha
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Behavior/neurological Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vocalization | 1 supporting dataset | Pmpcaem1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Pmpcaem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| absent vibrissae | 1 supporting dataset | Pmpcaem1(IMPC)J | heterozygote | Early adult | 1.67x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pmpcaem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased circulating calcium level | 1 supporting dataset | Pmpcaem1(IMPC)J | heterozygote | Early adult | 2.58x10-5 |
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External links
No external links available for Pmpca.
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| Pmpcaem1(IMPC)J | Exon Deletion | | mouse |
| Pmpcatm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pmpcatm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Pmpcatm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pmpcatm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |