Rnf148 | ring finger protein 148

GeneMGI:1918550Synonyms: 4933432M07Rik, Greul3

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



kyphosis	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.05x10^-5
decreased locomotor activity	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.1x10^-8
decreased thigmotaxis	2 supporting datasets	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.34x10^-7
cryptorchism	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.14x10^-7
decreased circulating serum albumin level	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.4x10^-6
abnormal spine curvature	1 supporting dataset	Rnf148^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.64x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf148.

Associated images

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Histopathology

There is no histopathology data found for Rnf148.

IMPC related publications

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External links

No external links available for Rnf148.

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*Rnf148^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Rnf148^{tm378004(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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