Slc29a3 | solute carrier family 29 (nucleoside transporters), member 3

GeneMGI:1918529Synonyms: 4933435C21Rik, Ent3

Physiological systems

22 / 24 physiological systems tested

17 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Digestive/alimentary Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Limbs/digits/tail Nervous system Liver/biliary system Respiratory system Behavior/neurological Skeleton

5 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:58Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



enlarged lymph nodes	2 supporting datasets	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased hematocrit	1 supporting dataset	Slc29a3^{em1(IMPC)Wtsi}	homozygote	Early adult	4.58x10^-48
enlarged spleen	2 supporting datasets	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Slc29a3^{em1(IMPC)Wtsi}	homozygote	Early adult	5.75x10^-16
abnormal spleen morphology	2 supporting datasets	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Slc29a3^{em1(IMPC)Wtsi}	homozygote	Early adult	1.25x10^-29
small seminal vesicle	1 supporting dataset	Slc29a3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc29a3.

Associated images

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Histopathology

There is no histopathology data found for Slc29a3.

IMPC related publications

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External links

No external links available for Slc29a3.

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*Slc29a3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Slc29a3^{em1(IMPC)Wtsi}*	Point Mutation	‌	mouse
*Slc29a3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Slc29a3^{tm48176(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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