Enkur | enkurin, TRPC channel interacting protein
Physiological systems
22 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Integument Growth/size/body region Behavior/neurological Craniofacial Cardiovascular system
15 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Enkurem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Enkurem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Enkurem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Enkurem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| abnormal facial morphology | 1 supporting dataset | Enkurem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| abnormal head shape | 1 supporting dataset | Enkurem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Enkurem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Enkurem1(IMPC)Mbp | heterozygote | Early adult | 1.04x10-6 |
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Human diseases caused by Enkur mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Enkur.
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| Enkurem1(IMPC)Mbp | Exon Deletion | | mouse |
| Enkurtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Enkurtm34117(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |