Rimklb | ribosomal modification protein rimK-like family member B

GeneMGI:1918325Synonyms: NAAGS, 4931417E21Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



hyperactivity	9 supporting datasets	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.7x10^-13
increased grip strength	2 supporting datasets	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	9.82x10^-11
hyperactivity	8 supporting datasets	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	2.34x10^-9
increased heart weight	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.95x10^-5
abnormal sleep behavior	2 supporting datasets	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.1x10^-6
increased exploration in new environment	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	5.46x10^-6
increased bone mineral content	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	2.99x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.61x10^-5
decreased total body fat amount	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	8.87x10^-6
male infertility	1 supporting dataset	Rimklb^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rimklb.

Associated images

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Histopathology

There is no histopathology data found for Rimklb.

IMPC related publications

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External links

No external links available for Rimklb.

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*Rimklb^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Rimklb^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rimklb^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Rimklb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rimklb^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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