Prss55 | serine protease 55

GeneMGI:1918287Synonyms: 4933401F05Rik

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	2 supporting datasets	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged seminal vesicle	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.63x10^-6
decreased heart rate	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.11x10^-5
abnormal heart morphology	2 supporting datasets	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Prss55^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss55.

Associated images

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Histopathology

There is no histopathology data found for Prss55.

IMPC related publications

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External links

No external links available for Prss55.

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*Prss55^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Prss55^{tm113189(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Prss55^{tm113189(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Prss55^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell
*Prss55^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Prss55^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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