Trak2 | trafficking protein, kinesin binding 2

GeneMGI:1918077Synonyms: GRIF1, OIP98, +5 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Integument Vision/eye Behavior/neurological

16 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsTrak2em1(IMPC)MbphomozygoteEarly adult1.88x10-13 
decreased anxiety-related response1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adult7.44x10-16 
abnormal behavior1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adult2.1x10-13 
abnormal lymph node morphology1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetTrak2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trak2em1(IMPC)MbpExon Deletionmouse
Trak2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Trak2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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