Dclk2 | doublecortin-like kinase 2

GeneMGI:1918012Synonyms: 6330415M09Rik, Click-II, +1 more

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total body fat amount1 supporting datasetDclk2em1(IMPC)JhomozygoteEarly adult3.34x10-5 
increased lean body mass1 supporting datasetDclk2em1(IMPC)JhomozygoteEarly adult2.05x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Dclk2em1(IMPC)JExon Deletionmouse
Dclk2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dclk2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dclk2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Dclk2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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