Dock4 | dedicator of cytokinesis 4

GeneMGI:1918006Synonyms: 6330411N01Rik, EST N28122

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Reproductive system Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal startle reflex	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	1.04x10^-5
increased grip strength	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	9.84x10^-5
abnormal behavior	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	3.42x10^-6
decreased thigmotaxis	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	3.42x10^-6
decreased anxiety-related response	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	6.6x10^-7
enlarged uterus	1 supporting dataset	Dock4^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dock4.

Associated images

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Histopathology

There is no histopathology data found for Dock4.

IMPC related publications

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External links

No external links available for Dock4.

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*Dock4^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Dock4^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Dock4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes