Sugp1 | SURP and G patch domain containing 1
Physiological systems
22 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Embryo Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
11 No significant impact
2 Not tested
Data collections
Gene metrics:19Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged kidney | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| enlarged spleen | 2 supporting datasets | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Sugp1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 2 supporting datasets | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Sugp1em1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal freezing behavior | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | Early adult | 7.12x10-7 | ||
| no spontaneous movement | 1 supporting dataset | Sugp1em1(IMPC)Mbp | heterozygote | E18.5 | N/A * |
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Human diseases caused by Sugp1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Sugp1.
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| Sugp1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Sugp1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sugp1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |