Fbxo33 | F-box protein 33

GeneMGI:1917861Synonyms: 5730501N20Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Fbxo33^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.94x10^-7
increased circulating alanine transaminase level	1 supporting dataset	Fbxo33^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.31x10^-5
absent pinna reflex	1 supporting dataset	Fbxo33^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.1x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo33.

Associated images

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Histopathology

There is no histopathology data found for Fbxo33.

IMPC related publications

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External links

No external links available for Fbxo33.

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*Fbxo33^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Fbxo33^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fbxo33^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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