Zc3h11a | zinc finger CCCH type containing 11A
Physiological systems
22 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Immune system Integument Endocrine/exocrine gland Embryo Nervous system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system
11 No significant impact
2 Not tested
Data collections
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal coat/hair pigmentation | 2 supporting datasets | Zc3h11aem1(IMPC)Mbp | heterozygote | Late adult | 8.25x10-6 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Zc3h11aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| spina bifida | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| decreased hemoglobin content | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | Early adult | 1.17x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | Early adult | 1.01x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| decreased hematocrit | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | Early adult | 3.81x10-5 | ||
| cataract | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | Late adult | 1.52x10-5 | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| decreased erythrocyte cell number | 1 supporting dataset | Zc3h11aem1(IMPC)Mbp | heterozygote | Early adult | 9.33x10-6 |
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External links
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| Zc3h11aem1(IMPC)Mbp | Exon Deletion | | mouse |