Lrrc56 | leucine rich repeat containing 56
Physiological systems
18 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Respiratory system Cardiovascular system
11 No significant impact
6 Not tested
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal heart position or orientation | 2 supporting datasets | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal heartbeat | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | 1.22x10-6 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | 6.07x10-10 | ||
| abnormal lung morphology | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased body length | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | 5.48x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Lrrc56em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Lrrc56 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Lrrc56.
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| Lrrc56em1(IMPC)Tcp | Exon Deletion | | mouse |
| Lrrc56tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Lrrc56tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Lrrc56tm42331(L1L2_Pgk_PM) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |