Lrrc56 | leucine rich repeat containing 56

GeneMGI:1917802Synonyms: 5730427C23Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Respiratory system Cardiovascular system

11 No significant impact

6 Not tested

Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal heart position or orientation2 supporting datasetsLrrc56em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal heartbeat1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adult1.22x10-6 
increased circulating alanine transaminase level1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adult6.07x10-10 
abnormal lung morphology1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased body length1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adult5.48x10-5 
enlarged lymph nodes1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetLrrc56em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrrc56em1(IMPC)TcpExon Deletionmouse
Lrrc56tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lrrc56tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lrrc56tm42331(L1L2_Pgk_PM)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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