Taf15 | TATA-box binding protein associated factor 15

GeneMGI:1917689Synonyms: TAFII68, Taf2n, +2 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Vision/eye Hematopoietic system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetTaf15em1(IMPC)MbphomozygoteEarly adultN/A * 
increased lymphocyte cell number1 supporting datasetTaf15em1(IMPC)MbphomozygoteEarly adult7.23x10-6 
abnormal skin morphology2 supporting datasetsTaf15em1(IMPC)MbphomozygoteEarly adultN/A * 
increased fasting circulating glucose level1 supporting datasetTaf15em1(IMPC)MbphomozygoteEarly adult7.88x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Taf15em1(IMPC)MbpExon Deletionmouse
Taf15tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Taf15tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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