Ica1l | islet cell autoantigen 1-like

GeneMGI:1917625Synonyms: 1700030B17Rik, Als2cr15, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Growth/size/body region Digestive/alimentary Vision/eye Cardiovascular system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged cecum2 supporting datasetsIca1ltm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetIca1ltm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetIca1ltm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ica1ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ica1ltm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ica1ltm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Ica1ltm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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