Bag5 | BCL2-associated athanogene 5

GeneMGI:1917619Synonyms: 4930405J06Rik, 1600025G07Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Nervous system Vision/eye

16 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
abnormal vitreous body morphology1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
abnormal eye morphology1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adult7.59x10-6 
anophthalmia1 supporting datasetBag5em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bag5em1(IMPC)MbpWhole-gene deletionmouse
Bag5tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bag5tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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