Bag5 | BCL2-associated athanogene 5
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Nervous system Vision/eye
16 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal brain morphology | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged testis | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | 5.99x10-5 | ||
| abnormal eye morphology | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | 7.59x10-6 | ||
| anophthalmia | 1 supporting dataset | Bag5em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Bag5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Bag5.
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| Bag5em1(IMPC)Mbp | Whole-gene deletion | | mouse |
| Bag5tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Bag5tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |