Secisbp2l | SECIS binding protein 2-like
Physiological systems
17 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Behavior/neurological Skeleton Cardiovascular system
9 No significant impact
7 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased startle reflex | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Early adult | 3.27x10-10 | ||
increased circulating cholesterol level | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 7.08x10-7 | ||
decreased total body fat amount | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 1.49x10-6 | ||
increased lean body mass | 2 supporting datasets | Secisbp2lem1(IMPC)J | homozygote | Late adult | 6.57x10-8 | ||
increased aggression | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Early adult | 4.37x10-5 | ||
increased bone mineral content | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 2.64x10-6 | ||
increased heart rate | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 2.26x10-7 | ||
decreased circulating aspartate transaminase level | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 1.13x10-7 | ||
increased grip strength | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 3.86x10-6 | ||
abnormal hindlimb morphology | 1 supporting dataset | Secisbp2lem1(IMPC)J | homozygote | Late adult | 1.51x10-5 |
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External links
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Secisbp2lem1(IMPC)J | Exon Deletion | | mouse |
Secisbp2ltm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Secisbp2ltm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |