Secisbp2l | SECIS binding protein 2-like

GeneMGI:1917604Synonyms: 3110001I20Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteEarly adult3.27x10-10 
increased circulating cholesterol level1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult7.08x10-7 
decreased total body fat amount1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult1.49x10-6 
increased lean body mass2 supporting datasetsSecisbp2lem1(IMPC)JhomozygoteLate adult6.57x10-8 
increased aggression1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteEarly adult4.37x10-5 
increased bone mineral content1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult2.64x10-6 
increased heart rate1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult2.26x10-7 
decreased circulating aspartate transaminase level1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult1.13x10-7 
increased grip strength1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult3.86x10-6 
abnormal hindlimb morphology1 supporting datasetSecisbp2lem1(IMPC)JhomozygoteLate adult1.51x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Secisbp2lem1(IMPC)JExon Deletionmouse
Secisbp2ltm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Secisbp2ltm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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