Secisbp2l | SECIS binding protein 2-like

GeneMGI:1917604Synonyms: 3110001I20Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased startle reflex	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Early adult	3.27x10^-10
increased circulating cholesterol level	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	7.08x10^-7
decreased total body fat amount	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	1.49x10^-6
increased lean body mass	2 supporting datasets	Secisbp2l^em1(IMPC)J	homozygote	Late adult	6.57x10^-8
increased aggression	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Early adult	4.37x10^-5
increased bone mineral content	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	2.64x10^-6
increased heart rate	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	2.26x10^-7
decreased circulating aspartate transaminase level	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	1.13x10^-7
increased grip strength	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	3.86x10^-6
abnormal hindlimb morphology	1 supporting dataset	Secisbp2l^em1(IMPC)J	homozygote	Late adult	1.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Secisbp2l.

Associated images

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Histopathology

There is no histopathology data found for Secisbp2l.

IMPC related publications

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External links

No external links available for Secisbp2l.

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*Secisbp2l^em1(IMPC)J*	Exon Deletion	‌	mouse
*Secisbp2l^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Secisbp2l^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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