Fuz | fuzzy planar cell polarity protein

GeneMGI:1917550Synonyms: b2b1273Clo, 2600013E07Rik

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Vision/eye Nervous system Craniofacial Mortality/aging Cardiovascular system

12 No significant impact

2 Not tested

Gene metrics:20Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

syndactyly1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsFuzem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal tail morphology1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
edema1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal craniofacial morphology1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
hemorrhage1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
cleft palate1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
anophthalmia1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
polydactyly1 supporting datasetFuzem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal neural tube morphology1 supporting datasetFuzem1(IMPC)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fuzem1(IMPC)MbpExon Deletionmouse
Fuztm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Fuztm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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