Dazap1 | DAZ associated protein 1

GeneMGI:1917498Synonyms: 2410042M16Rik, mPrrp

Physiological systems

24 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

17 No significant impact

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetDazap1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
decreased total body fat amount2 supporting datasetsDazap1em1(IMPC)CcpczheterozygoteEarly adult8.88x10-6 
increased lean body mass2 supporting datasetsDazap1em1(IMPC)CcpczheterozygoteEarly adult1.51x10-11 
abnormal heart morphology1 supporting datasetDazap1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetDazap1em1(IMPC)CcpczhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance1 supporting datasetDazap1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased eosinophil cell number1 supporting datasetDazap1em1(IMPC)CcpczheterozygoteEarly adult1.66x10-5 
decreased locomotor activity1 supporting datasetDazap1em1(IMPC)CcpczheterozygoteEarly adult8.63x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dazap1em1(IMPC)CcpczInter-exon deletionmouse
Dazap1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dazap1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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