Ppil3 | peptidylprolyl isomerase (cyclophilin)-like 3

GeneMGI:1917475Synonyms: 2310076N22Rik, 2510026K04Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating free fatty acids level	1 supporting dataset	Ppil3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.38x10^-5
increased circulating cholesterol level	1 supporting dataset	Ppil3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.66x10^-7
increased circulating HDL cholesterol level	1 supporting dataset	Ppil3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.82x10^-5
abnormal bone structure	1 supporting dataset	Ppil3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.13x10^-5
absent pinna reflex	1 supporting dataset	Ppil3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.45x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppil3.

Associated images

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Histopathology

There is no histopathology data found for Ppil3.

IMPC related publications

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External links

No external links available for Ppil3.

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*Ppil3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ppil3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ppil3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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