Fam162a | family with sequence similarity 162, member A

GeneMGI:1917436Synonyms: 2310056P07Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult5.36x10-8 
abnormal retina morphology1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult3.17x10-5 
persistence of hyaloid vascular system1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult5.62x10-7 
abnormal vitreous body morphology1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult4.69x10-6 
abnormal retina vasculature morphology1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult7.02x10-9 
decreased prepulse inhibition2 supporting datasetsFam162atm1b(EUCOMM)HmguhomozygoteEarly adult4.43x10-5 
cataract1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult3.76x10-6 
abnormal lens morphology1 supporting datasetFam162atm1b(EUCOMM)HmguhomozygoteEarly adult1.8x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam162atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Fam162atm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Fam162atm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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