Metrn | meteorin, glial cell differentiation regulator

GeneMGI:1917333Synonyms: 1810034B16Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Hematopoietic system

15 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetMetrnem1(IMPC)MbphomozygoteEarly adultN/A * 
increased neutrophil cell number1 supporting datasetMetrnem1(IMPC)MbphomozygoteEarly adult4.27x10-6 
abnormal spleen morphology1 supporting datasetMetrnem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetMetrnem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetMetrnem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Metrn mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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