Esrp1 | epithelial splicing regulatory protein 1
Physiological systems
22 / 24 physiological systems tested
12 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Skeleton Craniofacial Cardiovascular system Mortality/aging Renal/urinary system
10 No significant impact
2 Not tested
Data collections
Gene metrics:18Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal placenta vasculature | 1 supporting dataset | Esrp1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Esrp1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Esrp1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| decreased bone mineral density | 1 supporting dataset | Esrp1em1(IMPC)Mbp | heterozygote | Early adult | 1.97x10-5 | ||
| abnormal placenta morphology | 1 supporting dataset | Esrp1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Esrp1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Esrp1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal blood vessel morphology | 1 supporting dataset | Esrp1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| facial cleft | 1 supporting dataset | Esrp1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Esrp1em1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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External links
No external links available for Esrp1.
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| Esrp1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Esrp1tm169(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |