Ptcd3 | pentatricopeptide repeat domain 3

GeneMGI:1917206Synonyms: 2810422B04Rik, 2610034F17Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Ptcd3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Ptcd3^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
impaired pupillary reflex	1 supporting dataset	Ptcd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.23x10^-10
increased mean corpuscular hemoglobin	1 supporting dataset	Ptcd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.28x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Ptcd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.17x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptcd3.

Associated images

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Histopathology

There is no histopathology data found for Ptcd3.

IMPC related publications

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External links

No external links available for Ptcd3.

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*Ptcd3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ptcd3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes