Ttc39b | tetratricopeptide repeat domain 39B

GeneMGI:1917113Synonyms: 9130422G05Rik, 1810054D07Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral density1 supporting datasetTtc39btm1e(EUCOMM)WtsihomozygoteEarly adult9.29x10-5 
increased bone mineral content1 supporting datasetTtc39btm1e(EUCOMM)WtsiheterozygoteEarly adult1.06x10-5 
decreased circulating triglyceride level1 supporting datasetTtc39btm1e(EUCOMM)WtsiheterozygoteEarly adult3.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ttc39btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ttc39btm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
mouse
Ttc39btm36268(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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