Eif1ad | eukaryotic translation initiation factor 1A domain containing

GeneMGI:1917110Synonyms: 2010003J03Rik, Eif1ad1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Mortality/aging

13 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetEif1adtm1b(EUCOMM)HmguhomozygoteE9.5N/A * 
decreased lean body mass2 supporting datasetsEif1adtm1b(EUCOMM)HmguheterozygoteEarly adult3.82x10-8 
increased large unstained cell number1 supporting datasetEif1adtm1b(EUCOMM)HmguheterozygoteEarly adult1.94x10-5 
embryonic lethality prior to tooth bud stage1 supporting datasetEif1adtm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetEif1adtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eif1adtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Eif1adtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Eif1adtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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