Pold4 | polymerase (DNA-directed), delta 4

GeneMGI:1916995Synonyms: 2410012M21Rik, DNA polymerase delta smallest subunit p12, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetPold4em1(IMPC)JhomozygoteEarly adult1.58x10-7 
decreased circulating calcium level1 supporting datasetPold4em1(IMPC)JhomozygoteEarly adult3.26x10-8 
decreased circulating glucose level1 supporting datasetPold4em1(IMPC)JhomozygoteEarly adult5.41x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pold4em1(IMPC)JExon Deletionmouse
Pold4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pold4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pold4tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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