Tm2d2 | TM2 domain containing 2

GeneMGI:1916992Synonyms: 2410018G23Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging Craniofacial

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

edema1 supporting datasetTm2d2em1(IMPC)BayhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTm2d2em1(IMPC)BayhomozygoteEarly adultN/A * 
prenatal lethality1 supporting datasetTm2d2em1(IMPC)BayhomozygoteE18.5N/A * 
decreased startle reflex1 supporting datasetTm2d2em1(IMPC)BayheterozygoteLate adult1.45x10-6 
abnormal craniofacial morphology1 supporting datasetTm2d2em1(IMPC)BayhomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tm2d2em1(IMPC)BayExon Deletionmouse
Tm2d2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tm2d2tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Tm2d2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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