Nkiras1 | NFKB inhibitor interacting Ras-like protein 1

GeneMGI:1916971Synonyms: KBRAS1, 2400004O09Rik

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

20 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetNkiras1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetNkiras1em1(IMPC)CcpczhomozygoteEarly adult9.59x10-5 
microphthalmia1 supporting datasetNkiras1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nkiras1em1(IMPC)CcpczExon Deletionmouse
Nkiras1tm403005(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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