Camsap3 | calmodulin regulated spectrin-associated protein family, member 3

GeneMGI:1916947Synonyms: 2310057J16Rik, Nezha

Physiological systems

18 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging

7 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:30Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased blood urea nitrogen level	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.97x10^-5
abnormal auditory brainstem response	5 supporting datasets	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.19x10^-10
increased circulating thyroxine level	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.01x10^-5
decreased hemoglobin content	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.5x10^-6
trunk curl	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.62x10^-5
abnormal cornea morphology	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.82x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.54x10^-23
increased total body fat amount	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.47x10^-6
decreased circulating cholesterol level	1 supporting dataset	Camsap3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.3x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Camsap3.

Associated images

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Histopathology

There is no histopathology data found for Camsap3.

IMPC related publications

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External links

No external links available for Camsap3.

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*Camsap3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Camsap3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Camsap3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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