Ndufaf5 | NADH:ubiquinone oxidoreductase complex assembly factor 5

GeneMGI:1916737Synonyms: 2310003L22Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Ndufaf5^em1(IMPC)Bay	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Ndufaf5^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal locomotor behavior	1 supporting dataset	Ndufaf5^em1(IMPC)Bay	heterozygote	Early adult	7.96x10^-8
decreased exploration in new environment	1 supporting dataset	Ndufaf5^em1(IMPC)Bay	heterozygote	Early adult	1.34x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ndufaf5.

Associated images

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Histopathology

There is no histopathology data found for Ndufaf5.

IMPC related publications

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External links

No external links available for Ndufaf5.

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*Ndufaf5^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Ndufaf5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ndufaf5^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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